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Technical notes from projects I built: what problem each repo solved, how the workflow was designed, and what the results showed.

Workflow diagram linking TCGA BRCA metadata, methylation clocks, immune scores, RNA expression, and subtype classification
Jun 18, 2024 7 min read Featured

Classifying Breast Cancer Subtypes with Epigenetic Aging and Immune Multi-Omics

A project story about combining DNA methylation clocks, immune deconvolution, RNA expression, and methylation features to study PAM50 breast cancer subtype classification.

Multi-OmicsBreast CancerMachine LearningRPython
Read article Repo: BRCA multi-omics
ESM model result plots showing prediction versus ground truth, ROC curve, and score distributions
Nov 12, 2024 8 min read Featured

Using ESM Protein Language Models to Study APP Variant Effects

A deep-learning project comparing ESM scoring methods against experimental APP deep mutational scanning data, including epistasis and synthetic fitness landscape analysis.

Protein MLESMDeep LearningPyTorchVariant Effects
Read article Repo: ESM-DeepLearning
StrataDock application run screen showing docking configuration and live terminal output
May 1, 2025 7 min read Featured

StrataDock: Building a Modular Molecular Docking Workstation

A practical docking workstation that wraps receptor preparation, ligand handling, pocket selection, Vina/GNINA docking, validation, reporting, and Streamlit UI into one repeatable workflow.

Molecular DockingStreamlitVinaGNINADrug Discovery
Read article Repo: StrataDock
Bactoflow WGS workflow diagram from raw reads through QC, assembly, annotation, screening, and reports
Apr 9, 2024 6 min read Featured

Bactoflow-WGS: A Reproducible Bacterial Genome Analysis Pipeline

A Snakemake workflow for bacterial whole-genome sequencing that moves from raw reads to assembly, QC, annotation, screening, pangenome analysis, and phylogeny.

SnakemakeBacterial WGSGenomicsReproducibilityConda
Read article Repo: bactoflow-wgs

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